Article
Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism
Registro en:
MARINHO, Penélope Saldanha et al. Case report: SARS-CoV-2 mother-to-child transmission and fetal death associated with severe placental thromboembolism. Frontiers in Medicine, v. 8, n. 677001, p. 1-9, 16 Aug. 2021.
2296-858X
10.3389/fmed.2021.677001
2296-858X
Autor
Marinho, Penélope Saldanha
Cunha, Antonio José Ledo Alves da
Chimelli, Leila
Avvad-Portari, Elyzabeth
Andreiuolo, Felipe da Matta
Oliveira-Szejnfeld, Patrícia Soares de
Mendes, Mayara Abud
Gomes, Ismael Carlos
Souza, Letícia Rocha Q.
Guimarães, Marilia Zaluar
Goldman, Suzan Menasce
Oliveira, Mariana Barros Genuíno de
Rehen, Stevens
Amim Jr., Joffre
Tovar-Moll, Fernanda
Prata-Barbosa, Arnaldo
Resumen
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. SARS-CoV-2 infection during pregnancy is not usually associated with significant adverse effects. However, in this study, we report a fetal death associated with mild COVID-19 in a 34-week-pregnant woman. The virus was detected in the placenta and in an unprecedented way in several fetal tissues. Placental abnormalities (MRI and anatomopathological study) were consistent with intense vascular malperfusion, probably the cause of fetal death. Lung histopathology also showed signs of inflammation, which could have been a contributory factor. Monitoring inflammatory response and coagulation in high-risk pregnant women with COVID-19 may prevent unfavorable outcomes, as shown in this case.