Abstract: Organizations around the world require a sound process of change management to innovate and remain competitive over time. Change and knowledge management needs to be supported with the right tools to overcome the challenges of transformations and transitions in the business models and processes of diverse organizations. Steering boards can use enterprise architecture (EA) to implement new knowledge management initiatives in their strategic planning. EA allows companies to model the current situation (as-is models) of the organization and the desired future scenarios (to-be models) and to establish road maps to enable adequate transformations. Different frameworks exist in the market that support the management of organizations, for example: Control Objectives for Information and Related Technologies (COBIT), Information Technology Infrastructure Library (ITIL), quality models such as the one proposed by the European Foundation for Quality Management (EFQM) and systems such as the Balanced Scorecard (BSC) are widely used for the management of business and information technologies (IT). However, EA is not widely used with the other mentioned tools. This paper analyzes EA as a tool for change and knowledge management and compares its functionality with other frameworks in the market. The analysis performed in this paper checks if EA can be used and is compatible with other frameworks. To answer this question, an analysis of the most important processes, good practices, perspectives and tools provided by each framework was performed.