Artigo
Serum DHEA-S increases in dogs naturally infected with Ehrlichia canis
Registro en:
Research In Veterinary Science. Oxford: Elsevier Sci Ltd, v. 100, p. 18-20, 2015.
0034-5288
10.1016/j.rvsc.2015.04.010
WOS:000356558100004
3254990612451836
Autor
Rondelli, M. C. H. [UNESP]
Munhoz, T. D.
Catandi, P. B.
Freschi, C. R. [UNESP]
Palacios Junior, R. J. G.
Machado, R. Z. [UNESP]
Tinucci-Costa, M. [UNESP]
Resumen
Adrenocortical disturbances are expected in canine ehrlichiosis due to the immunological challenges caused by infection and consequent inflammation. Thus, this study aimed to evaluate the occurrence of adrenocortical hormonal alterations in dogs naturally infected with Ehrlichia canis (n=21) as positively confirmed by the presence of anti-E. cartis antibodies (Dot-ELISA) and nested PCR (nPCR). Serum dehydroepiandrosterone sulfate (DHEA-S) concentrations were assessed via ELISA before and one hour after ACTH stimulation. Another 10 healthy dogs were subjected to the same stimulation protocol and used as controls. The results revealed that baseline and post-ACTH DHEA-S concentrations were significantly greater in sick dogs, regardless of gender, and this finding illustrates the stress induced by naturally acquired ehrlichiosis in dogs. (C) 2015 Elsevier Ltd. All rights reserved. Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Univ Estadual Paulista, Dept Vet Clin &Surg, Fac Ciencias Agr &Vet, BR-14884900 Jaboticabal, SP, Brazil Ctr Univ Barao de Maua, BR-14031580 Ribeirao Preto, SP, Brazil Autonomous Vet, BR-15800190 Catanduva, SP, Brazil Univ Estadual Paulista, Fac Ciancias Agr &Vet, Dept Vet Pathol, BR-14884900 Jaboticabal, SP, Brazil Autonomous Vet, BR-04326080 Sao Paulo, SP, Brazil Department of Veterinary Clinic and Surgery, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Via de Acesso Prof. Paulo Donato Castellane, Jaboticabal, SP 14884-900, Brazil Department of Veterinary Pathology, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Via de Acesso Prof. Paulo Donato Castellane, Jaboticabal, SP 14884-900, Brazil FAPESP: 2010/02676-3 FAPESP: 2010/11630-7