Land- use change (LUC) can impact soil quality. In semi- arid areas of Brazil, impacts of LUC need to be understood for better soil management. This study evaluated the impact of LUC on soil organic carbon (SOC), nitrogen (N), and phosphorus (P) dis-tributions through the soil profile and stocks of a Haplic- Cambisol in the Brazilian Semi- arid region. Three land- use systems (LUS) were investigated: agricultural man-agement (30years), regeneration under controlled grazing (25years) after 5years arable management, and native dry forest. Soil contents of P, total C, total N, and N fractions were used to calculate stocks and their stoichiometric ratios for layers 0? 5, 5? 10, 10? 20, and 20? 40cm. Data from these LUS were compared using Kruskal? Wallis non- parametric tests. Changes to soil microbial biomass reflected the sub-stantially reduced SOC concentration and stock in managed soils compared with that of the natural dry forest area. Total N stock was not affected by LUC, although increases in nitrate and ammonium offset a significantly reduced organic N fraction in the agricultural area. The largest P stock was found in agricultural land, followed by the grazed fallow regeneration site. LUC significantly influenced the stoichiomet-ric ratio of C, N, and P, with the change from Caatinga to agriculture affecting the equilibrium between organic residues? input and mineralization. LUC resulted in sig-nificant changes to C, N, and P stocks, which did not recover to the original values, even after 25years of regeneration under controlled grazing.