| dc.description.abstract | Collapse of exclusively bronchial pathways in dogs is rarely reported in the literature,
as most studies focus on tracheal collapse. There is no specific and curative treatment, but
only therapies and recommendations focused on clinical signs. Thus, the treatment is
considered frustrating for both the owner and the veterinarian. Stanozolol is a drug with
anabolic properties, capable of promoting tissue growth, stimulating chondrocytes and
increasing the synthesis of collagen and chondroitin sulfate however its use is poorly explored
in veterinary medicine. The aim of this study is to provide a literature review about bronchial
collapse, which is still poorly understood and described; and report a case of a canine with
that disease, which was submitted to a clinical treatment with stanozolol for 112 days. The
frequency of coughing, described by the tutors, was the main evaluation parameter, and
showed a significant reduction in the first month.It remained intermediate until the end of
treatment; and after that, it became accentuated again. Fortnightly hematological
examinations were performed. There was an increase of Alanine Aminotransferase (ALT)
enzyme, which normalized after reducing the frequency of the drug to once a day and
discontinuing the concomitant use of a bronchodilator; however, it fluctuated again, for no
apparent reason, later. Although it is not possible to determine the influences of frequency and
dose of stanozolol and theophylline administration together, the use of this medication seems
to be promising. More studies are needed to evaluate the effectiveness of this steroid in the
treatment of bronchial collapse in dogs. | |
