Resenha
Cytotoxic T cells and mycobacteria
Fecha
2001-04-01Registro en:
Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 197, n. 1, p. 11-18, 2001.
0378-1097
10.1111/j.1574-6968.2001.tb10575.x
WOS:000167980100002
Autor
Silva, Celio L.
Bonato, Vania LD
Lima, Karla M.
Coelho-Castelo, Arlete AM
Faccioli, Lucia H.
Sartori, Alexandrina
De Souza, Ana O.
Leao, Sylvia Cardoso [UNIFESP]
Institución
Resumen
How the immune system kills Mycobacterium tuberculosis is still a puzzle. the classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.