Artigo
FCGR3B*03 allele inheritance pattern in Brazilian families and some new variants of gene FCGR3B
Fecha
2012-03-01Registro en:
Transfusion. Malden: Wiley-Blackwell, v. 52, n. 3, p. 629-634, 2012.
0041-1132
10.1111/j.1537-2995.2011.03326.x
WOS:000301229200026
Autor
Terzian, Claudia C. N.
Chiba, Akemi K.
Santos, Viviani C.
Silva, Neusa P.
Bordin, Jose O. [UNIFESP]
Institución
Resumen
BACKGROUND: the FCGR3B gene encoding the FcyRIIIb receptor for immunoglobulin G has three polymorphic forms known as HNA-1a, HNA-1b, and HNA-1c, encoded by the alleles FCGR3B*01, FCGR3B*02, and FCGR3B*03, respectively. It is not clear whether the inheritance of the FCGR3B*03 allele, which encodes the HNA-1c, is linked or not to the other two alleles. the objective of this study was to identify the inheritance pattern of the FCGR3B*03 allele in Brazilians.