Esta investigaci?n plantea el uso del AFE (ADS1299), su fabricante expone unos par?metros de montaje superficial que sirvieron como base para el dise?o del PCB en Corel DRAW. La revisi?n bibliogr?fica abre un camino referente a la aplicaci?n del campo de estudio, como se observa en esta revisi?n del estado del arte se han desarrollado prototipos en los cuales el ADS1299 se proyecta como una pieza fundamental para la captura de la se?ales biom?dicas y dependiendo de la aplicaci?n existen diversas tarjetas utilizadas como maestro que permiten la comunicaci?n y visualizaci?n. Se obtiene un PCB con tama?o adecuado, utilizando materiales de superficie que brindan menor ruido al sistema, cuyo valor econ?mico es accesible. El proceso de ingenier?a inversa aplicado a las tarjetas maestro-esclavo de la Texas Intruments, sirvi? de gu?a significativa para los par?metros de construcci?n del hardware que hasta aqu? no se hab?an tenido en cuenta, como consecuencia la selecci?n del arduino DUE (maestro) de la placa ya desarrollada. Las se?ales de test permitieron un claro funcionamiento del sistema en conjunto, posteriormente se realiz? la captura de se?ales biom?dicas evalu?ndolas mediante el software Matlab, validando la informaci?n con el kit de la Texas instruments; se examinan unos resultados con se?ales iguales en un 98%, y en otra posterior validaci?n con el software de ?determinaci?n del nivel de concentraci?n? elaborado por los estudiantes de la Universidad de Ibagu?; presento se?ales biom?dicas optimas en amplitud, frecuencia y con un nivel m?nimo de ruido, que cotejaron el funcionamiento de mencionado programa.This research proposes the use of AFE (ADS1299), its manufacturer exposes some surface mounting parameters that served as the basis for the design of the PCB in Corel DRAW. The bibliographic review opens a path regarding the application of the field of study, as can be seen in this review of the state of the art prototypes have been developed in which the ADS1299 is projected as a fundamental piece for the capture of biomedical signals and depending on There are several cards used as a teacher that allow communication and visualization. A PCB with adequate size is obtained, using surface materials that provide less noise to the system, whose economic value is accessible. The reverse engineering process applied to the master-slave cards of the Texas Intruments, served as a significant guide for the hardware construction parameters that had not been taken into account, as a result of the selection of the arduino DUE (master) of the already developed plate. The test signals allowed a clear operation of the system as a whole, subsequently the capture of biomedical signals was performed by evaluating them through Matlab software, validating the information with the Texas instruments kit; results with equal signals in 98% are examined, and in another validation with the ?concentration level determination? software prepared by the students of the University of Ibagu?; I present optimal biomedical signals in amplitude, frequency and with a minimum level of noise, which checked the operation of this program.