info:eu-repo/semantics/article
Stable impulsive zone model predictive control for type 1 diabetic patients based on a long‐term model
Autor
González, Alejandro
Rivadeneira, Pablo
Ferramosca, Antonio
Magdelaine, Nicolas
Moog, Claude
Institución
Resumen
In this work, the problem of regulating blood glucose (glycemia) in type I diabetic patients is studied by means of an impulsive zone model predictive control (iZMPC), which bases its predictions on a novel long‐term glucose‐insulin model. Taking advantage of the impulsive version of the model—which features real‐life properties of diabetes patients that some other popular models do not—the given control guarantees the stability under moderate‐to‐severe plant‐model mismatch and disturbances. Long‐term scenarios—including meals and physiological parameter variations—are simulated and the results are satisfactory as every hyperglycemic and hypoglycemic episodes are suitably controlled. Fil: Institute of Technological Development for the Chemical Industry (INTEC), CONICET‐Universidad Nacional del Litoral (UNL), Güemes 3450, (3000) Santa Fe, Argentina. Fil: Universidad Nacional de Colombia, Facultad de Minas, Grupo GITA, Medellín, Colombia Fil: Facultad Regional de Reconquista, CONICET ‐ Universidad Tecnológica Nacional (UTN), Santa Fe, Argentina Fil: LS2N, UMR CNRS 6004, Nantes, France Fil: LS2N, UMR CNRS 6004, Nantes, France Peer Reviewed