Purpose: To present our experience of slit-lamp laser photocoagulation with a pediatric quadraspheric contact lens for the treatment of retinopathy of prematurity (ROP). Material and methods: 8 eyes of 4 premature babies with threshold ROP were consecutively treated under general anesthesia by means of blue-green argon laser photocoagulation delivered through a table mounted slit-lamp and a wide field contact lens specially designed for infants. Three of the treated eyes had a zone, disease, 2 a posterior zone II disease and 3 a zone II disease. Mean follow-up was 13 months. Results: Early complete regression of the neovascular proliferations and plus disease was observed in all the treated eyes (100%) without apparent sequela. In only one eye that had zone I disease a mild and small peripheral vitreous hemorrhage was observed. Neither cataract nor posterior synechia was observed. A discrete and transient badly hypothermia occurred only in one case. Comments and conclusions: This study shows the efficacy and precision of slit-lamp argon laser photocoagulation through a quadraspheric contact lens in ROP, with a very low rate of complications, and with a magnificent and comfortable visualization of all the structures to be treated. Each retinal burn was easily and very precisely placed from the ridge to the ora serrata in 360°with only a slight to moderate tilting of the wide field lens and without the need of scleral depression.Fil: Urrets Zavalía, Julio. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaFil: Urrets Zavalía, Enrique Alberto. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaFil: Iros, M. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina