Fil: Callejo, Raquel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Zheng, Han. Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control, Changping, Beijing, PR; China.Fil: Du, Pengcheng. Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, PR; China.Fil: Prieto, Mónica A. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Xu, Jianguo. Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control, Changping, Beijing, PR; China.Fil: Zielinski, Gustavo. Instituto Nacional de Tecnologia Agropecuaria (INTA), Marcos Juárez, Córdoba; Argentina.Fil: Auger, Jean-Philippe. Swine and Poultry Infectious Disease Center, (CRIPA), Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Quebec; Canada.Fil: Gottschalk, Marcelo. Swine and Poultry Infectious Disease Center, (CRIPA), Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Quebec; Canada.Streptococcus suis serotype 2 is an important swine pathogen and emerging zoonotic agent causing meningitis and septicemia/septic shock. Strains are usually virulent (Eurasia) or of intermediate/low virulence (North America). Very few data regarding human and swine isolates from South America are available.