info:eu-repo/semantics/article
Understanding epidemics from mathematical models: Details of the 2010 dengue epidemic in Bello (Antioquia, Colombia)
Registro en:
0307-904X
10.1016/j.apm.2016.11.022
Autor
Arboleda Sánchez, Sair Orieta
Lizarralde Bejarano, Diana Paola
Puerta Yepes, María Eugenia
Institución
Resumen
ABSTRACT: Dengue is the most threatening vector-borne viral disease in Colombia. At the moment,
there is no treatment or vaccine available for its control or prevention; therefore, the main
measure is to exert control over mosquito population. To reduce the economic impact of
control measures, it is important to focus on specific characteristics related to local dengue
epidemiology at the local level, and know the main factors involved in an epidemic. To this
end, we used a mathematical model based on ordinary differential equations and experimental data regarding mosquito populations from Bello (Antioquia, Colombia) to simulate the epidemic occurred in 2010. The results showed that the parameters to which the incidence of dengue cases are most sensitive are the biting and mortality rates of adult mosquitoes as well as the virus transmission probabilities. Finally, we found that the Ba-
sic Reproductive Number (R0) of this epidemic was between 1.5 and 2.7, with an infection
force () of 0.061, meaning that R0 values slightly above one are sufficient to result in a significant dengue outbreak in this region. COL0007865