Digital vs. Film Fundus Photography for Research Grading of Diabetic Retinopathy Severity

dc.creatorFlórez Arango, José Fernando
dc.creatorLi, Helen K.
dc.creatorHubbard, Larry D.
dc.creatorDanis, Ronald P.
dc.creatorEsquivel, Adol
dc.creatorKrupinski, Elizabeth A.
dc.creatorFerrier, Nicola J.
dc.date2022-12-25T20:07:27Z
dc.date2022-12-25T20:07:27Z
dc.date2010
dc.date.accessioned2023-08-28T19:52:27Z
dc.date.available2023-08-28T19:52:27Z
dc.identifierLi HK, Hubbard LD, Danis RP, Esquivel A, Florez-Arango JF, Ferrier NJ, Krupinski EA. Digital versus film Fundus photography for research grading of diabetic retinopathy severity. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5846-52. doi: 10.1167/iovs.09-4803.
dc.identifier0146-0404
dc.identifierhttps://hdl.handle.net/10495/32977
dc.identifier10.1167/iovs.09-4803
dc.identifier1552-5783
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8470048
dc.descriptionABSTRACT: Purpose.: To assess agreement between digital and film photography for research classification of diabetic retinopathy severity. Methods.: Digital and film photographs from a 152-eye cohort with a full spectrum of Early Treatment Diabetic Retinopathy Study (ETDRS) severity levels were assessed for repeatability of grading within each image medium and for agreement on ETDRS discrete severity levels, ascending severity thresholds, and presence or absence of diabetic retinopathy index lesions, between digital and 35-mm slides (film). Digital photographs were color balanced to match film. Results.: There was substantial agreement (κ = 0.61, κw [linear weighted] = 0.87) in classification of ETDRS diabetic retinopathy severity levels between digital images and film. Marginal homogeneity analyses found no significant difference in frequency distributions on the severity scale (P = 0.21, Bhapkar test). The κ results ranged from 0.72 to 0.95 for presence or absence of eight ascending diabetic retinopathy severity thresholds. Repeatability of grading between readers viewing digital images was equal to or better than that obtained with film (pair-wise interreader κ for digital images ranged from 0.47 to 0.57 and for film from 0.43 to 0.57. The κ results for identifying diabetic retinopathy lesions ranged from moderate to almost perfect. Moderate agreement of intraretinal microvascular abnormalities and venous beading between digital images and film accounted for slightly lower concordance for severity thresholds ≥47 and for slightly lower interreader agreement within digital and film images at severity thresholds ≥43 and ≥47. Conclusions.: Under controlled circumstances, digital photography can equal the reliability of 35-mm slides for research classification of ETDRS severity level.
dc.descriptionCOL0036212
dc.format7
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherAssociation for Research in Vision and Ophthalmology
dc.publisherInformed
dc.publisherSan Luis, Estados Unidos
dc.relationInvest. Ophthalmol. Vis. Sci.
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAnciano
dc.subjectAged
dc.subjectAnciano de 80 o más Años
dc.subjectAged, 80 and over
dc.subjectDiabetes Mellitus Tipo 1
dc.subjectDiabetes Mellitus, Type 1
dc.subjectDiabetes Mellitus Tipo 2
dc.subjectDiabetes Mellitus, Type 2
dc.subjectTécnicas de Diagnóstico Oftalmológico
dc.subjectDiagnostic Techniques, Ophthalmological
dc.subjectReproducibilidad de los Resultados
dc.subjectReproducibility of Results
dc.subjectProcesamiento de Señales Asistido por Computador
dc.subjectSignal Processing, Computer-Assisted
dc.subjectÍndice de Severidad de la Enfermedad
dc.subjectSeverity of Illness Index
dc.titleDigital vs. Film Fundus Photography for Research Grading of Diabetic Retinopathy Severity
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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