Changes in the haematological parameters produced by exposure of rainbow trout(oncorhynchus mykiss) to chitosan acetate

BULLETIN OF THE EUROPEAN ASSOCIATION OF FISH PATHOLOGISTS;
Bull. Eur. Assoc. Fish Pathol.

dc.creatorCARDENAS-TRIVIÑO, GALO
dc.creatorCABRERA, G.
dc.creatorSILVA, V.
dc.creatorVALENZUELA, A.
dc.date2017-04-27T18:51:03Z
dc.date2022-07-07T02:20:24Z
dc.date2017-04-27T18:51:03Z
dc.date2022-07-07T02:20:24Z
dc.date2003
dc.date.accessioned2023-08-22T03:41:06Z
dc.date.available2023-08-22T03:41:06Z
dc.identifier0
dc.identifierD99I1076
dc.identifierD99I1076
dc.identifierWOS:000185279600006
dc.identifier0108-0288
dc.identifierhttps://hdl.handle.net/10533/197268
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8316109
dc.descriptionChitosan is a derivate of chitin, one of the most abundant polysaccharides in nature. In aquaculture, chitosan has been used as a flocculant in water recirculation systems with good results, but recent studies have shown that chitosan acetate may be toxic, producing branchial damage and death in trout. To improve the understanding of the toxic mechanism of chitosan on Oncorhyncus mykiss we exposed juveniles (60 g) for 1-2h to chitosan acetate at 10 mg/L and 0.1 mg/L. Fish exposed to the highest concentration of chitosan acetate experienced a rise in the ventilation rate (74%), the hematocrit (39%) and in the immature erythrocyte counts (157%). The number of mature erythrocytes as well as hemoglobin were also higher than in control fish but not statistically different. Simultaneously, a decrease in the mean corpuscular haemoglobin concentration (37%) was detected in relation to control measurements. These results and the death of fish after 30 to 60 min of exposure to 10 mg/L are evidence that chitosan induced respiratory stress causes death by hypoxia. We proposed that the structural characteristics of the molecule would facilitate its interaction with residues of sialic acid in the mucous-secreting epithelia.
dc.description0
dc.description0
dc.descriptionFONDEF
dc.description0
dc.description0
dc.description4
dc.descriptionFONDEF
dc.description23
dc.languageENG
dc.publisherEUR ASSOC FISH PATHOLOGISTS
dc.relationinstname: Conicyt
dc.relationreponame: Repositorio Digital RI2.0
dc.relationinstname: Conicyt
dc.relationreponame: Repositorio Digital RI2.0
dc.relationinfo:eu-repo/grantAgreement/Fondef/D99I1076
dc.relationinfo:eu-repo/semantics/dataset/hdl.handle.net/10533/93477
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleChanges in the haematological parameters produced by exposure of rainbow trout(oncorhynchus mykiss) to chitosan acetate
dc.titleBULLETIN OF THE EUROPEAN ASSOCIATION OF FISH PATHOLOGISTS
dc.titleBull. Eur. Assoc. Fish Pathol.
dc.typeArticulo
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.coverageABERDEEN


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