El presente trabajo de investigación fue monitorear la contaminación de los lixiviados generados en el relleno sanitario de la empresa pública EMASA del cantón Santa Elena, lo que permitió obtener los siguientes resultados de los análisis realizados por el laboratorio acreditado y la aplicación de la ecuación de T-Student. DBO5 42,700 mg/L; DQO, 5 9381,2 mg/L, SS 816 mg/L; SD 29,200 mg/L, pH 8,28, T 25,8 °C; Pb 0,5 mg/L; Hg 0,5 mg/L, NTU 1,142; Color 86,000 mg/L y olor no tienes una medida. Estos valores sobrepasan los niveles de contaminación como establece I Libro VI del TULSMA para descargas de aguas residuales en cuerpos de agua dulce. El de tratamiento físico-químico aplicado en esta investigación, se obtuvo una efectividad de remoción de 78% de sólidos suspendido y 22% de líquido presente en los lixiviados. Palabras clave: Monitoreo de lixiviado, Residuos Sólidos Urbanos, Relleno sanitario, Contaminación de suelo, Empresa Pública EMASA. Abstract The aim of this research was to monitor the contamination of leachates generated at sanitary landfill of EMASA public company in Santa Elena city, it allowed to get the following results from analyzes carried out by accredited laboratory and application of the T-Student equation. BOD5 42,700 mg / L; COD, 5 9381.2 mg / L, SS 816 mg / L; SD 29,200 mg / L, pH 8.28, T 25.8 ° C; Pb 0.5 mg / L; Hg 0.5 mg / L, NTU 1.142; Color 86,000 mg / L, however smell does not have a measure. These values exceed the contamination level as established Book VI of TULSMA for discharges of wastewater into bodies of fresh water. The physical-chemical treatment applied in this investigation was obtained a removal effectiveness of 78% in suspended solids and 22% of liquid present in the leachates. Keywords: Leachate monitoring: Urban Solid Waste, Sanitary landfill, Soil pollution, EMASA Public Company. Fecha de recepción: 28 de mayo de 2020; Fecha de aceptación: 08 de julio de 2020; Fecha de publicación: 09 de julio de 2020.The aim of this research was to monitor the contamination of leachates generated at sanitary landfill of EMASA public company in Santa Elena city, it allowed to get the following results from analyzes carried out by accredited laboratory and application of the T-Student equation. BOD5 42,700 mg / L; COD, 5 9381.2 mg / L, SS 816 mg / L; SD 29,200 mg / L, pH 8.28, T 25.8 ° C; Pb 0.5 mg / L; Hg 0.5 mg / L, NTU 1.142; Color 86,000 mg / L, however smell does not have a measure. These values exceed the contamination level as established Book VI of TULSMA for discharges of wastewater into bodies of fresh water. The physical-chemical treatment applied in this investigation was obtained a removal effectiveness of 78% in suspended solids and 22% of liquid present in the leachates. Keywords: Leachate monitoring: Urban Solid Waste, Sanitary landfill, Soil pollution, EMASA Public Company.