Tanning industry is an important economical activity in some provinces of our country. Nevertheless, due to the inner characteristics of this process, pollution in every environmental component is generated. One of the components which is mainly affected is water due to the discharge of effluents with high concentration of organic matter, suspended solids, in different condition of acidity or alkalinity and with toxic elements as sulfide and chromium. These last ones are capable to put in risk the integrity of the environment as well as human health. This investigation tries to establish the conditions which are adequate to develop the physicochemical treatment of the main effluents in tanning industry: unhairing, tanning and soaking.La industria de la curtiembre constituye una actividad económica importante en ciertas provincias del país, sin embargo, por las características propias de este proceso genera contaminación en los diferentes componentes ambientales. Uno de los mayormente afectados es el agua con la descarga de efluentes con elevadas concentraciones de materia orgánica, sólidos suspendidos, en diferentes condiciones de acidez o alcalinidad y elementos tóxicos como el sulfuro y el cromo, que ponen en riesgo la integridad del ambiente y la salud de las personas.