The present clinical case is about a male patient who is admitted to the medical home because of an acute brain injury causing him to have an acute respiratory distress syndrome. The aim of the investigation was to determine the epidemiological profile and clinical manifestations in adult patients with acute respiratory distress syndrome associated with acute brain injury. The data obtained were given by physical examination and assessments. Pending the results of complementary examinations such as chest radiography and blood tests, suspected pulmonary infiltration, lung reduction and edema in the upper and lower extremities were confirmed. The patient was referred to the ICU but showed no improvement, and cyanosis was present. After that, arterial blood gases were ordered to verify the decrease in carbon dioxide, and mechanical ventilation was managed, with the addition of intravenous drugs for early recovery. The patient's vital signs were established to normal levels over the days, and the appropriate treatment for a patient with ARDS due to ACL is pressure-controlled ventilation.The present clinical case is about a male patient who is admitted to the medical home because of an acute brain injury causing him to have an acute respiratory distress syndrome. The aim of the investigation was to determine the epidemiological profile and clinical manifestations in adult patients with acute respiratory distress syndrome associated with acute brain injury. The data obtained were given by physical examination and assessments. Pending the results of complementary examinations such as chest radiography and blood tests, suspected pulmonary infiltration, lung reduction and edema in the upper and lower extremities were confirmed. The patient was referred to the ICU but showed no improvement, and cyanosis was present. After that, arterial blood gases were ordered to verify the decrease in carbon dioxide, and mechanical ventilation was managed, with the addition of intravenous drugs for early recovery. The patient's vital signs were established to normal levels over the days, and the appropriate treatment for a patient with ARDS due to ACL is pressure-controlled ventilation.El presente caso clínico trata de un paciente de sexo masculino que ingresa a la casa de salud por una lesión cerebral aguda ocasionándole a su vez un síndrome de distrés respiratorio agudo. La investigación tuvo como objetivo determinar el perfil epidemiológico y las manifestaciones clínicas en pacientes adultos con síndrome de distrés respiratorio agudo asociado a lesión cerebral aguda. Los datos obtenidos fueron dados por el examen físico y evaluaciones. En la espera de los resultados de los exámenes complementarios como la radiografía torácica y exámenes de sangre, se confirmaron las sospechas de infiltración pulmonar, reducción de pulmones y edemas en las extremidades superiores e inferiores. En el seguimiento al paciente, este es derivado a UCI pero no presenta mejorías, y hay presencia de cianosis, posterior a eso se ordena realizarle gasometrías arteriales para verificar la disminución del dióxido de carbono, y el manejo de ventilación mecánica, añadiéndole la aplicación de fármacos intravenosos para su pronta recuperación. Concluyendo que el paciente con el paso de los días fue estableciendo sus signos vitales a los niveles normales, y que el tratamiento adecuado para un paciente con SDRA por LCA es la ventilación controlada por presión.