Physiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials

dc.creatorMontalvo González, Efigenia
dc.creatorVillagrán De la Mora, Blanca Zuamí
dc.creatorGonzález Torres, Yesica Sughey
dc.creatorIñiguez Muñoz, Laura Elena
dc.creatorIsiordia Espinoza, Mario Alberto
dc.creatorRuvalcaba Gómez, José Martín
dc.creatorArteaga Garibay, Ramón Ignacio
dc.creatorAcosta, José Luis
dc.creatorGonzález Silva, Napoleón
dc.creatorAnaya Esparza, Luis Miguel
dc.date2022-09-20T18:33:58Z
dc.date2022-09-20T18:33:58Z
dc.date2022-04
dc.date.accessioned2023-07-21T21:45:50Z
dc.date.available2023-07-21T21:45:50Z
dc.identifierMontalvo-González, E.; Villagrán, Z.; González-Torres, S.; Iñiguez-Muñoz, L.E.; Isiordia-Espinoza, M.A.; Ruvalcaba-Gómez, J.M.; Arteaga-Garibay, R.I.; Acosta, J.L.; González-Silva, N.; Anaya-Esparza, L.M. Physiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials. Pharmaceuticals 2022, 15, 464. https://doi.org/10.3390/ph15040464
dc.identifier1424-8247
dc.identifierhttps://doi.org/10.3390/ph15040464
dc.identifierhttp://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1413
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7752885
dc.descriptionArtículo
dc.descriptionHibiscus sabdariffa Linn. Malvaceae (HS) is characterized by its edible calyxes. The HS calyxes are widely used for cosmetic, food, and medicinal applications. According to ethnobotanical evidence, decoction, infusion, or maceration extracts from HS calyxes have been used in folk medicine to treat many ailments. Moreover, several in vitro and in vivo studies have demonstrated the pharmacological properties and potential human health benefits of HS consumption. On the other hand, the evaluation of the physiological effects and health benefits of HS in clinical studies is most challenging. Therefore, this narrative review summarizes and discusses the physiological effects and health benefits of HS calyxes reported in clinical trials. Preparations obtained from HS calyxes (extracts, infusions, decoction, teas, beverages, capsules, and pills) are used as non-pharmacological therapies to prevent/control diverse chronic non-communicable diseases. The most-reported HS health benefits are its antihypertensive, antidyslipidemic, hypoglycemic, body fat mass reduction, nephroprotective, antianemic, antioxidant, anti-inflammatory, and anti-xerostomic activities; these effects are associated with the phytochemicals found in HS. Moreover, no adverse effects were reported during the clinical trials. However, clinical studies exhibited some limitations; thus, further studies are required to validate the clinical efficacy of HS in large-scale studies with higher doses and a good experimental design.
dc.languageen
dc.publisherMDPI
dc.relationPharmaceuticals;2022, 15 (4), 464
dc.subjecthibiscus sabdariffa
dc.subjectcalyx
dc.subjectclinical trials
dc.subjecthealth benefits
dc.subjectbioactive compounds
dc.titlePhysiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials
dc.typeArticle


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