Lipoproteomics: Methodologies and Analysis of Lipoprotein-Associated Proteins along with the Drug Intervention

Drug Design - Novel Advances in the Omics Field and Applications

dc.creatorTorres Romero, Julio Cesar
dc.creatorLara Riegos, Julio César
dc.creatorEstrella Parra, Edgar Antonio
dc.creatorFernández Sánchez, Verónica
dc.creatorArana Argáez, Victor E
dc.creatorUc Colli, Sushally
dc.creatorPeña Rico, Miguel Ángel
dc.creatorRamírez Camacho, Mario Alberto
dc.creatorPonce Regalado, Maria Dolores
dc.creatorÁlvarez Sánchez, María Elizbeth
dc.date2022-07-12T17:35:08Z
dc.date2022-07-12T17:35:08Z
dc.date2021-06
dc.date.accessioned2023-07-21T21:45:35Z
dc.date.available2023-07-21T21:45:35Z
dc.identifierTorres-Romero, J. C. , Lara-Riegos, J. C. , Parra, E. A. E. , Sánchez, V. F. , Arana-Argáez, V. E. , Uc-Colli, S., Peña-Rico, M. Á. , Ramírez-Camacho, M. A. , Regalado, M. D. P. , & Alvarez-Sánchez, M. E. (2020). Lipoproteomics: Methodologies and Analysis of Lipoprotein-Associated Proteins along with the Drug Intervention. In (Ed.), Drug Design - Novel Advances in the Omics Field and Applications. IntechOpen. https://doi.org/10.5772/intechopen.93634
dc.identifier978-1-78985-201-1
dc.identifier978-1-78984-753-6
dc.identifier978-1-78984-752-9
dc.identifierhttps://doi.org/10.5772/intechopen.93634
dc.identifierhttp://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/1376
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7752847
dc.descriptionCapítulo
dc.descriptionLipoproteins are specialized particles involved in the transport and distribution of hydrophobic lipids, as cholesterol and triglycerides, throughout the body. The lipoproteins exhibit a basic spherical shape as complexes of lipids and proteins, and these latter are known as apolipoproteins. Initially, the proteins associated with lipoproteins were recognized as integral or peripheral proteins that only maintain the dynamics and metabolism of lipoproteins. However, there exist many studies on different lipoproteins evidencing that the quantity and type of apolipoproteins and lipoprotein-associated proteins are diverse and could be associated with different lipoprotein function outcomes. Here, we summarized recent processes in the determination of apolipoproteins and lipoprotein-associated proteins profiles through a proteomic approach, analyzing the major methods available and are used to achieve this. We also discuss the relevance of these lipoproteomic analyses on the human disease outcomes.
dc.languageen
dc.publisherIndonesia International Institute for Life Sciences, Indonesia
dc.subjectlipoproteins
dc.subjectlipoproteomic
dc.subjectproteomic
dc.subjecthigh density lipoproteins (HDL)
dc.subjectmass spectrometry (MS)
dc.titleLipoproteomics: Methodologies and Analysis of Lipoprotein-Associated Proteins along with the Drug Intervention
dc.titleDrug Design - Novel Advances in the Omics Field and Applications
dc.typeBook chapter


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