Association of serotonin transporter gene polymorphism 5-HTTLPR and depressive disorder in a Mexican population

Brief Association Letters

dc.creatorPeralta Leal, Valeria
dc.creatorLeal Ugarte, Evelia
dc.creatorMeza Espinoza, Juan Pablo
dc.creatorGutiérrez Angulo, Melva
dc.creatorHernández Benítez, Catalina T.
dc.creatorGarcía Rodríguez, Alfonso
dc.creatorDávalos Rodríguez, Ingrid P.
dc.creatorGonzales, Enrique
dc.creatorDurán González, Jorge
dc.date2015-07-21T19:27:27Z
dc.date2015-07-21T19:27:27Z
dc.date2012-10
dc.date.accessioned2023-07-21T21:39:28Z
dc.date.available2023-07-21T21:39:28Z
dc.identifierPeralta-Leal, V., Leal-Ugarte, E., Meza-Espinoza, J. P., Gutiérrez-Angulo, M., Hernández-Benítez, C. T., García-Rodríguez, A., Durán-González, J. (2012). Association of serotonin transporter gene polymorphism 5-HTTLPR and depressive disorder in a Mexican population. Psychiatric Genetics, 22(5), 265–266. http://doi.org/10.1097/YPG.0b013e32834f3577
dc.identifier1473-5873
dc.identifierdoi: 10.1097/YPG.0b013e32834f3577
dc.identifierhttp://repositorio.cualtos.udg.mx:8080/jspui/handle/123456789/354
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7752037
dc.descriptionThe interplay of genetic variations with environmental influences is widely recognized as the causal mechanism behind depression (Lohoff, 2010). The SLC6A4 gene that codes for the serotonin transporter (5-HTT) is especially expressed in the cortical and limbic area; therefore, its allelic variants have been involved in behavior and depression disorders. Among these variants, there are two located 1400 bp upstream of the transcription start site; a short (S) and a long (L) variant of 14 and 16 copies, respectively, of a 44-bp repeat element (Collier et al., 1996). Current information suggests that these alleles regulate the 5-HTT expression differently, especially the S allele, which may play a key role in the etiology of depressive disorder (Goldman et al., 2010).
dc.descriptionFacultad de Medicina e Ingeniería en Sistemas Computacionales, Universidad Autónoma de Tamaulipas, H. Matamoros Tamaulipas, Centro Universitario de los Altos, Universidad de Guadalajara. Doctorado en Gene´ tica Humana, CUCS, Universidad de Guadalajara, División de Genética, CIBO, Instituto Mexicano del Seguro Social (IMSS), Guadalajara Jalisco, Hospital General de Sub Zona de Medicina General No. 33, Instituto Mexicano del Seguro Social (IMSS). Delegación Veracruz Norte, San Andrés Veracruz, México Department of Biological Sciences, Center of Biomedical Studies, University of Texas at Brownsville, Brownsville, Texas, USA Facultad de Medicina e Ingeniería en Sistemas Computacionales, Universidad Autónoma de Tamaulipas. Matamoros, Tamaulipas, México
dc.languageen
dc.publisherPsychiatric Genetics
dc.relationPsychiatric Genetics;October 2012 - Volume 22 - Issue 5 - p 265–266
dc.titleAssociation of serotonin transporter gene polymorphism 5-HTTLPR and depressive disorder in a Mexican population
dc.titleBrief Association Letters
dc.typeArticle


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