The lionfish is the first invasive species that came to the western Atlantic region to establish itself as an ecological and economic threat to coral ecosystems and commercially important consumption species. Fifteen specimens were collected in Quintana Roo, Mexico, to analyze the chemical composition of the lionfish (Pterois volitans) as a strategy to promote its consumption by the population. They were gutted, filleted, homogenized and chemically analyzed. The analyzed LF had an energetic protein content of 103.89 kcal 100 g-1 of the fillet (20.19%) and a fat percentage of 2.56%. The content of P, Ca, Na, K and Mg were 174.15, 26.09, 81.47, 339.73 and 30.27 mg 100 g-1, respectively. The most abundant essential amino acid was lysine (12.98 g 100 g-1 protein). The present work is important because it reports that the LF could be used as food with the right quantity and quality of protein, and its consumption would diminish its environmental impact.