This paper addresses the Flexible Job Shop Scheduling Problem (FJSSP) where the objective is to minimize the makespan. We develop a parallel hybrid Differential Evolution (DE) algorithm to tackle this problem. A random key representation of the FJSSP is adopted, which requires a very simple conversion mechanism to obtain a feasible schedule. This allows the DE algorithm to work on the continuous domain to explore the problem space of the discrete FJSSP. Moreover, a simple local search algorithm is embedded in the DE framework to balance the exploration and exploitation by enhancing the local searching ability. In addition, parallelism of the DE operations is included to improve the efficiency of whole algorithm. Experiments confirm the significant improvement achieved by integrating the propositions introduced in this study. Additional, test results show that our algorithm is competitive when compared with most existing approaches for the FJSSP.XX Workshop Agentes y Sistemas Inteligentes.Red de Universidades con Carreras en Informática