The odontogenic keratocysts tumor is a benign intraosseous uni- or multicystic tumor, characterized by the presence of stratified squamous parakeratinized epithelium, with a aggressive potential and infiltrative behavior. Its importance lies in its high rate of recurrence. We report a case of a male patient of 46 years, asymptomatic, with a volume augmentation of the right side of the face. After the clinical, histopathological and radiographic examination, it was diagnosed as Odontogenic Keratocysts Tumor. Surgical treatment was performed with satisfactory results.El tumor odontogénico queratoquístico es un tumor intraóseo benigno uni o multiquístico caracterizado por la presencia de un epitelio escamoso estratificado paraqueratinizado, que tiene un potencial agresivo y un comportamiento infiltrativo. Su importancia se basa en su alta tasa de recurrencia. Se reporta un caso clínico de un paciente masculino de 46 años, asintomático, con aumento de volumen facial del lado derecho. Luego de los exámenes clínico, histopatológico y radiográfico se diagnosticó: Tumor Odontogénico Queratoquístico. Se realizó tratamiento quirúrgico obteniendo resultados satisfactorios.