Universidad del Desarrollo (Chile): últimos ingresos
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El Taller Integrado de Diseño como espacio de aprendizaje y simulador de vuelo
(2022)¿Cómo y en qué momento dar sentido de la realidad a un estudiante de Diseño? ¿En qué espacios se pueden poner en práctica en contextos reales los conocimientos y competencias adquiridas por un estudiante ? ¿Qué procesos y ... -
Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
(2022)Human induced pluripotent stem cell (hiPSC)-derived hair-bearing skin organoids offer exciting new possibilities for modeling diseases like epidermolysis bullosa (EB). These inherited diseases affect 1 in 30,000 people ... -
Duration of effectiveness of vaccines against SARS-CoV-2 infection and COVID-19 disease: results of a systematic review and meta-regression
(2022)Background: Knowing whether COVID-19 vaccine effectiveness wanes is crucial for informing vaccine policy, such as the need for and timing of booster doses. We aimed to systematically review the evidence for the duration ... -
A cien años de la Bauhaus : conexiones, ideales y materialización de un proyecto utópico
(2022)En el presente artículo se exponen algunas ideas resultantes de las reflexiones en torno a la Bauhaus en cursos de Historia del Diseño realizados durante los últimos años. El diseño, como disciplina, es relativamente nuevo, ... -
PLA/CaO nanocomposites with antimicrobial and photodegradation properties
(2022)CaO nanoparticles sized ca. 26 nm were organically modified with oleic acid (Ol-CaO), and both were incorporated into PLA at concentrations of 5 and 8 wt.% by a melting process. Modification of nanoparticles improved the ... -
Antimicrobial Resistance Dynamics in Chilean Shigella sonnei Strains Within Two Decades: Role of Shigella Resistance Locus Pathogenicity Island and Class 1 and Class 2 Integrons
(2022)Shigellosis is an enteric infectious disease in which antibiotic treatment is effective, shortening the duration of symptoms and reducing the excretion of the pathogen into the environment. Shigella spp., the etiologic ... -
Digital Therapeutics Care Utilizing Genetic and Gut Microbiome Signals for the Management of Functional Gastrointestinal Disorders: Results From a Preliminary Retrospective Study
(2022)Diet and lifestyle-related illnesses including functional gastrointestinal disorders (FGIDs) and obesity are rapidly emerging health issues worldwide. Research has focused on addressing FGIDs via in-person cognitive-behavioral ... -
Transmission of gram‑negative antibiotic‑resistant bacteria following difering exposure to antibiotic‑resistance reservoirs in a rural community: a modelling study for bloodstream infections
(2022)Exposure to community reservoirs of gram-negative antibiotic-resistant bacteria (GN-ARB) genes poses substantial health risks to individuals, complicating potential infections. Transmission networks and population dynamics ... -
Phenotypic and Genotypic Characterization of Macrolide, Lincosamide and Streptogramin B Resistance among Clinical Methicillin-Resistant Staphylococcus aureus Isolates in Chile
(2022)Macrolides, lincosamides, and type B streptogramins (MLSB) are important therapeutic options to treat methicillin-resistant Staphylococcus aureus (MRSA) infections; however, resistance to these antibiotics has been emerging. ... -
Key Role of Astrocytes in Postnatal Brain and Retinal Angiogenesis
(2022)Angiogenesis is a key process in various physiological and pathological conditions in the nervous system and in the retina during postnatal life. Although an increasing number of studies have addressed the role of endothelial ... -
Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo
(2022)Lack of type VII collagen (C7) disrupts cellular proteostasis yet the mechanism remains undescribed. By studying the relationship between C7 and the extracellular matrix (ECM)-associated proteins thrombospondin-1 (TSP1), ... -
Review of techniques useful for the assessment of sensory small fiber neuropathies: Report from an IFCN expert group.
(2022)Nerve conduction studies (NCS) are an essential aspect of the assessment of patients with peripheral neuropathies. However, conventional NCS do not reflect activation of small afferent fibers, including Aδ and C fibers. A ... -
Temporal Trends of Intravenous Thrombolysis Utilization in Acute Ischemic Stroke in a Prospective Cohort From 1998 to 2019: Modeling Based on Joinpoint Regression
(2022)Introduction: The frequency of intravenous thrombolysis (IVT) in acute ischemic stroke (AIS) is lower than it should be in several regions of the world. It is unclear what interventions can produce significant improvements ... -
Neutralizing antibodies induced by homologous and heterologous boosters in CoronaVac vaccines in Chile
(2023)Objectives:To determine the impact of a booster dose on the humoral response in individuals inoculated with a complete schedule of any SARS-CoV-2 vaccine, we evaluated the neutralizing antibody (NAb) titres of homologous ... -
Senescence Markers in Peripheral Blood Mononuclear Cells in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease
(2022)Recent studies suggest that cellular senescence plays a role in Alzheimer’s Disease (AD) pathogenesis. We hypothesize that cellular senescence markers might be tracked in the peripheral tissues of AD patients. Senescence ... -
Head shaking does not alter vestibulo ocular reflex gain in vestibular migraine
(2022)Vestibular Migraine (VM) is the most common cause of non-positional episodic vestibular symptoms. Patients with VM commonly report increased motion sensitivity, suggesting that vestibular responses to head movement may ... -
¿Cómo Conciliar la Libertad Religiosa con las Normas Antidiscriminación? Tres Mecanismos y sus Fundamentos en el Sistema Jurídico Chileno
(2022)Frente a los crecientes conflictos entre la libertad religiosa y la no discriminación, el artículo recurre a fuentes comparadas y domésticas para proponer tres mecanismos para su conciliación, todos los cuales gozan de ... -
Electroencephalographic response to transient adaptation of vestibular perception
(2022)When given a series of sinusoidal oscillations in which the two hemicycles have equal amplitude but asymmetric velocity, healthy subjects lose perception of the slower hemicycle (SHC), reporting a drift towards the faster ... -
The Impact of a Yoga-Based Mindfulness Intervention versus Psycho-Educational Session for Older Adults with Mild Cognitive Impairment: The Protocol of a Randomized Controlled Trial
(2022)Background: There is a global agreement in the medical community that a significant proportion of dementia cases could be prevented or postponed. One of the factors behind this agreement comes from scientific evidence ... -
Comparative In Vitro Activity of Ceftolozane/Tazobactam against Clinical Isolates of Pseudomonas aeruginosa and Enterobacterales from Five Latin American Countries
(2022)Background: Ceftolozane/tazobactam (C/T) is a combination of an antipseudomonal oxyiminoaminothiazolyl cephalosporin with potent in vitro activity against Pseudomonas aeruginosa and tazobactam, a known β-lactamase inhibitor. ...