dc.contributorMiranda-Díaz, A.G., Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Jalisco, Mexico; Hermosillo-Sandoval, J.M., Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico; Ortiz, G.G., Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico; Lizardi-García, D., Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Jalisco, Mexico; Cardona-Muñoz, E.G., Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Jalisco, Mexico; Pacheco-Moisés, F., Centro Universitario de Ciencias Exactas e Ingeniería, Universidad de Guadalajara, Jalisco, Mexico
dc.creatorMiranda-Diaz, A.G.
dc.creatorHermosillo-Sandoval, J.M.
dc.creatorOrtiz, G.G.
dc.creatorLizardi-Garcia, D.
dc.creatorCardona-Munoz, E.G.
dc.creatorPacheco-Moises, F.
dc.date.accessioned2015-11-19T18:57:21Z
dc.date.accessioned2023-07-04T03:42:06Z
dc.date.available2015-11-19T18:57:21Z
dc.date.available2023-07-04T03:42:06Z
dc.date.created2015-11-19T18:57:21Z
dc.date.issued2010
dc.identifierhttp://hdl.handle.net/20.500.12104/70710
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-77957943397&partnerID=40&md5=560888921881e954f4c087c94f9f41fc
dc.identifierhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=20575594
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7266742
dc.description.abstractBackground: post-cholecystectomy bile duct injuries are identified by the onset of jaundice as well as elevated bilirubin and alkaline phosphatase levels during the peri-operative period. It is unknown how serum oxidative stress markers are modified in patients with post-cholecystectomy bile duct injuries. Objective: to determine serum oxidative stress marker levels (lipid peroxidation by-products, nitrites/nitrates and total antioxidant capacity) in patients with post-cholecystectomy bile duct injuries. Patients and methods: a prospective, transversal and analytical study was designed with two groups. Group 1: 5 healthy volunteer subjects. Group 2: 52 patients with post-cholecystectomy bile duct injuries (43 female and 9 male). An elective bilio-digestive reconstruction was performed at week 8. The serum oxidative stress marker levels were quantified by colorimetric method. Results: patients with bile duct injuries had a significant increased serum lipid peroxides (malondialdehyde and 4-hydroxyalkenals) and nitric oxide metabolites (nitrites/nitrates) levels compared to the control group. In contrast, total antioxidant capacity in patients with bile duct injuries remained similar compared to healthy controls. Conclusions: the results show that oxidative stress is usually associated to bile duct injury. © 2010 ARÁN EDICIONES, S. L.
dc.relationRevista Espanola de Enfermedades Digestivas
dc.relation102
dc.relation6
dc.relation352
dc.relation356
dc.relationScopus
dc.relationMEDLINE
dc.relationScIELO
dc.relationWOS
dc.titleSerum oxidative stress is increased in patients with post cholecystectomy bile duct injury
dc.typeArticle


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