Serotonin uptake in the central nervous system of rats fed a corn-diet

dc.contributorBeas-Zárate, C., Facultad de Ciencias, Universidad de Guadalajara and División de Biología del Desarrollo, Unidad de Investigación Biomédica de Occidente, I.M.S.S., Guadalajara, JaliscoMéxico; Del Angel Meza, A.R., Facultad de Ciencias, Universidad de Guadalajara and División de Biología del Desarrollo, Unidad de Investigación Biomédica de Occidente, I.M.S.S., Guadalajara, JaliscoMéxico; Morales-Villagran, A., Facultad de Ciencias, Universidad de Guadalajara and División de Biología del Desarrollo, Unidad de Investigación Biomédica de Occidente, I.M.S.S., Guadalajara, JaliscoMéxico; Feria Velasco, A., Facultad de Ciencias, Universidad de Guadalajara and División de Biología del Desarrollo, Unidad de Investigación Biomédica de Occidente, I.M.S.S., Guadalajara, JaliscoMéxico
dc.contributorBeas-Zárate, Carlos., Universidad de Guadalajara. Facultad de Ciencias
dc.creatorBeas-Zárate, Carlos
dc.creatorDel Angel Meza, A.R.
dc.creatorMorales-Villagran, A.
dc.creatorFeria Velasco, A.
dc.date.accessioned2015-11-19T18:57:21Z
dc.date.accessioned2023-07-04T01:35:57Z
dc.date.available2015-11-19T18:57:21Z
dc.date.available2023-07-04T01:35:57Z
dc.date.created2015-11-19T18:57:21Z
dc.date.issued1988
dc.identifierhttp://hdl.handle.net/20.500.12104/70697
dc.identifier10.1016/0742-8413(88)90205-8
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0023893841&partnerID=40&md5=4bfb4a97f3dc1142c15b2e4cc4f934ce
dc.identifierhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med3&AN=2455617
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7258367
dc.description.abstract1. Endogenous serotonin (5-HT), 5-hydroxyindol acetic acid (5-HIAA) content and exogenous 5-HT uptake (Km and Vmax) were measured in different brain regions (cerebellum, diencephalon, brain stem and telencephalon) of rats fed with a corn diet and restricted protein (8%) diet during 6 weeks. 2. A reduction of 5-HT levels was found in all regions studied of animals fed a corn diet, whereas, 5-HIAA was only decreased in brain stem and diencephalon. 3. An important increase in Km and Vmax were registered in brain stem and diencephalon of protein restricted animals, whereas, an increase of 5-HT uptake affinity in cerebellum, brain stem and telencephalon (35, 42 and 33% respectively) was observed. Simultaneously, under corn diet conditions, the Vmax decreased 40, 30 and 34% respectively in those regions. 4. It is suggested that the brain stem was the more sensitive area under nutritional restricted conditions and the development of some possible compensatory mechanisms of the 5-HTergic system is discussed. © 1988.
dc.relationComparative Biochemistry and Physiology. Part C, Comparative
dc.relation89
dc.relation2
dc.relation173
dc.relation177
dc.relationScopus
dc.relationMEDLINE
dc.relationWOS
dc.titleSerotonin uptake in the central nervous system of rats fed a corn-diet
dc.typeArticle


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