Effect of Ginkgo biloba extract EGb 761 on the nonspecific and humoral immune responses in a hypothalamic-pituitary-adrenal axis activation model

dc.contributorVillase�or-Garc�a, M.M., Lab. Inmunofarmacologia Prod. Nat., Div. de Medicina Molecular CIBO-IMSS, Guadalajara, Jalisco, Mexico, Dpto. de Farmacobiolog�a, CUCEI Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Centro de Investigaci�n, Biom�dica de Occidente, IMSS, Sierra Mojada No. 800, C.P. 44340 Guadalajara, Jalisco, Mexico; Lozoya, X., Laboratorio de Plantas Medicinales, U. Invest. en Enferm. Neurologicas, C.M.N. Siglo XXI, M�xico, D.F., Mexico; Osuna-Torres, L., Laboratorio de Biotecnolog�a, Ctro. de Invest. Biomedica del Sur, IMSS, Cuernavaca, Morelos, Mexico; Viveros-Paredes, J.M., Lab. Inmunofarmacologia Prod. Nat., Div. de Medicina Molecular CIBO-IMSS, Guadalajara, Jalisco, Mexico; Sandoval-Ram�rez, L., Laboratorio de Bioqu�mica IV, Div. de Gen�tica Humana, IMSS, Guadalajara, Jalisco, Mexico; Puebla-P�rez, A.M., Lab. Inmunofarmacologia Prod. Nat., Div. de Medicina Molecular CIBO-IMSS, Guadalajara, Jalisco, Mexico, Dpto. de Farmacobiolog�a, CUCEI Universidad de Guadalajara, Guadalajara, Jalisco, Mexico
dc.creatorVillasenor-Garcia, M.M.
dc.creatorLozoya, X.
dc.creatorOsuna-Torres, L.
dc.creatorViveros-Paredes, J.M.
dc.creatorSandoval-Ramirez, L.
dc.creatorPuebla-Perez, A.M.
dc.date.accessioned2015-09-15T17:47:35Z
dc.date.accessioned2023-07-04T01:31:59Z
dc.date.available2015-09-15T17:47:35Z
dc.date.available2023-07-04T01:31:59Z
dc.date.created2015-09-15T17:47:35Z
dc.date.issued2004
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-3142604772&partnerID=40&md5=f3c60b011a8d9ba65c6fed665d63133e
dc.identifierhttp://hdl.handle.net/20.500.12104/40943
dc.identifier10.1016/j.intimp.2004.05.014
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7258104
dc.description.abstractWe evaluated the immune response of healthy control and stressed Wistar rats submitted to hypothalamic-pituitary-adrenal (HPA) axis activation. Rats were treated with Ginkgo biloba extract (EGb 761) orally (100 mg/kg per day for 7 days). EGb 761 stimulated the digestion index of peritoneal and alveolar macrophages (PM and AM) of stressed rats. Likewise, the cellular immune response measured using the delayed-type hypersensitivity response to sheep red blood cells (SRBC) and the humoral immune response (measured through an anti-SRBC response), were also restored in stressed rats. Thus, this G. biloba extract possesses immunostimulatory activity in addition to its broad spectrum of pharmacological effects. � 2004 Elsevier B.V. All rights reserved.
dc.relationScopus
dc.relationWOS
dc.relationInternational Immunopharmacology
dc.relation4
dc.relation9
dc.relation1217
dc.relation1222
dc.titleEffect of Ginkgo biloba extract EGb 761 on the nonspecific and humoral immune responses in a hypothalamic-pituitary-adrenal axis activation model
dc.typeArticle


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