And molecular genetic alterations: Colorectal cancer (CRC) [Cáncer colorrectal (CCR): Alteraciones genéticas y moleculares]

dc.contributorJuárez-Vázquez, C.I., Universidad de Guadalajara, Guadalajara, Jal, Mexico, División de Medicina Molecular, Centro de Investigation Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jal, Mexico; Rosales-Reynoso, M.A., División de Medicina Molecular, Centro de Investigation Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jal, Mexico
dc.creatorJuarez-Vazquez, C.I.
dc.creatorRosales-Reynoso, M.A.
dc.date.accessioned2015-09-15T17:20:04Z
dc.date.accessioned2023-07-03T22:43:31Z
dc.date.available2015-09-15T17:20:04Z
dc.date.available2023-07-03T22:43:31Z
dc.date.created2015-09-15T17:20:04Z
dc.date.issued2014
dc.identifierhttp://hdl.handle.net/20.500.12104/39491
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84901403630&partnerID=40&md5=3a22bd65c1742fae4529e791a9818d5d
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/7246589
dc.description.abstractThe aim of this review is to present a genetic and molecular overview of colorectal carcinogenesis (sporadic and hereditary origin) as a multistage process, where there are a number of molecular mechanisms associated with the development of colorectal cancer and genomic instability that allows the accumulation of mutations in proto-oncogenes and tumor suppressor genes, chromosomal instability, and methylation and microsatellite instability, and the involvement of altered expression of microRNAs' prognosis factors.
dc.relationScopus
dc.relationGaceta Medica de Mexico
dc.relation150
dc.relation2
dc.relation154
dc.relation164
dc.titleAnd molecular genetic alterations: Colorectal cancer (CRC) [Cáncer colorrectal (CCR): Alteraciones genéticas y moleculares]
dc.typeReview


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