Experimental Analyses Emphasize the Stability of the Meisenheimer Complex in a S N Ar Reaction Toward Trends in Reaction Pathways

dc.creatorCampodónico, Paola
dc.creatorOlivares, Belén
dc.creatorTapia, Ricardo A.
dc.date.accessioned2021-07-21T16:37:21Z
dc.date.accessioned2023-05-19T14:51:16Z
dc.date.available2021-07-21T16:37:21Z
dc.date.available2023-05-19T14:51:16Z
dc.date.created2021-07-21T16:37:21Z
dc.date.issued2020-07
dc.identifierFrontiers in Chemistry, 2020 Jul, vol.8: 583
dc.identifierhttps://doi.org/10.3389/fchem.2020.00583
dc.identifierhttp://hdl.handle.net/11447/4188
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/6302989
dc.description.abstractThe mechanism of SNAr reactions between 2-chloro-5-nitropyrimidine with primary and secondary alicyclic amines, respectively, have been studied by kinetic measurements. The kinetic data obtained in aqueous media opens a controversial discussion based on Brönsted-type plots analysis. The first approach based on the kinetic data reveals a non-catalyzed pathway. Then, the subtlety of the mathematical treatment of the kinetic data is discussed over a concerted or stepwise mechanism, respectively.
dc.languageen
dc.subjectBrönsted-type plots
dc.subjectMeisenheimer complex
dc.subjectSNAr reaction
dc.subjectBorder mechanisms
dc.subjectReaction mechanism
dc.titleExperimental Analyses Emphasize the Stability of the Meisenheimer Complex in a S N Ar Reaction Toward Trends in Reaction Pathways
dc.typeArticle


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