| dc.description.abstract | induced by food allergens, clinically characterized by symptoms of esophageal
dysfunction. Pathologically there is a predominant eosinophilic inflammation.
This disease is relatively new, and its definitions have evolved over time. Its
prevalence and incidence are increasing and causes clinical problems both in
children and adults. Its symptoms include food impaction, dysphagia, symptoms
that resemble gastroesophageal reflux, abdominal pain, and vomiting. It can also
have extra-digestive symptoms such as rhinosinusitis, chronic cough, recurrent
croup and hoarseness. EoE can be associated with other atopic conditions, such
as asthma, eczema and food allergies. The diagnosis is made by the analysis of
endoscopic biopsies (> 15 eosinophils per high power field). Proton pump inhibitors (PPIs) are currently accepted as a treatment for EoE. The clinical and
pathological improvement with the use PPIs ceased to be a criterion to define
Esophageal eosinophilia responsive to PPIs as a differential diagnosis, since this
condition is currently considered within the EoE spectrum. There are three main
treatment approaches for EoE: diet, drugs and dilation. Its diagnosis and early
treatment are key to avoid or delay its complications, such as stenosis and severe
esophageal dysfunction. | |
