Modeling Parkinson's Disease Heterogeneity to Accelerate Precision Medicine

dc.creatorOlivares, Gonzalo
dc.creatorOlguín, Patricio
dc.creatorKlein, Andrés
dc.date.accessioned2020-03-27T14:36:16Z
dc.date.accessioned2023-05-19T14:45:48Z
dc.date.available2020-03-27T14:36:16Z
dc.date.available2023-05-19T14:45:48Z
dc.date.created2020-03-27T14:36:16Z
dc.date.issued2019
dc.identifierTrends Mol Med. 2019 Dec;25(12):1052-1055. doi: 10.1016/j.molmed.2019.09.004.
dc.identifierhttp://hdl.handle.net/11447/3183
dc.identifierhttps://doi.org/10.1016/j.molmed.2019.09.004
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/6301389
dc.description.abstractmechanistic understanding of the diverse clinical manifestations of Parkinson's disease (PD) and variable patient response to treatments is lacking. Genetically diverse PD model organisms can be used to map modifier genes and understand clinically relevant phenotypes of varying severity. This strategy can accelerate the pace of discoveries for precision medicine purposes.
dc.languageen
dc.publisherElsevier Ltd.
dc.subjectParkinson’s disease
dc.subjectCustomized therapies
dc.subjectGenome-wide association studies
dc.subjectInbred animal organisms
dc.subjectModifier genes
dc.subjectPrecision medicine
dc.titleModeling Parkinson's Disease Heterogeneity to Accelerate Precision Medicine
dc.typePreprint


Este ítem pertenece a la siguiente institución