Articulo Revista Indexada
Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity
Autor
Guallar, María Pilar
Meiriño, Rosa
Donat-Vargas, Carolina
Jouvé, Nicolás
Soriano, Vicente (1)
Institución
Resumen
A relationship between the infecting dose and the risk of disease severity has not been demonstrated for SARS-CoV-2 infection. Here, we report three clusters of individuals that were potentially exposed to distinct inoculum in Madrid. Overall each group developed divergent clinical forms of COVID-19. Our data support that a greater viral inoculum at the time of SARS-CoV-2 exposure might determine a higher risk of severe COVID-19.