| dc.creator | Sepúlveda, Ester | |
| dc.creator | Rojas, Isolde | |
| dc.creator | Fernández, Eduardo | |
| dc.creator | Muñoz, Mirna | |
| dc.creator | Oñate, Angel | |
| dc.date | 2015-11-27T19:42:40Z | |
| dc.date | 2015-11-27T19:42:40Z | |
| dc.date | 2008 | |
| dc.identifier | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 105 | |
| dc.identifier | 0716-078X | |
| dc.identifier | http://repositoriodigital.ucsc.cl/handle/25022009/624 | |
| dc.description | Artículo de publicación ISI | |
| dc.description | Objective: The objective of this study was to assess if there is increased herpes simplex virus type 1 (HSV-1) salivary shedding in oncology pediatric patients with severe cytopenia (SC). Study design: HSV-1 was detected by real time PCR in saliva samples from oncology pediatric patients (n = 30) during SC and relative cytopenia (RC), and from healthy children (n = 27). Results: The frequency of HSV-1 positive saliva samples was higher in patients with SC as compared to controls (P < .05), and this frequency presented a significant reduction during RC periods (P < .02). The SC group positive for HSV-1 presented both a twofold increase in the neutrophil-to-lymphocyte ratio as compared with SC patients negative for HSV-1 (P < .05), and a positive correlation between neutrophil and lymphocyte counts (P < .05, R = 0.82, R2 = 0.67). This correlation was not found in oncology patients negative for HSV-1 during SC and RC. | |
| dc.language | en | |
| dc.publisher | Elsevier | |
| dc.rights | Atribucion-Nocomercial-SinDerivadas 3.0 Chile | |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| dc.source | http://goo.gl/QWRf37 | |
| dc.subject | Herpes simplex | |
| dc.subject | Virus type 1 | |
| dc.subject | Severe cytopenia | |
| dc.title | Effect of white cell counts on the presence of human herpes simplex virus type-1 in saliva of pediatric oncology patients | |
| dc.type | Article | |
