Artículos de revistas
Estudio ultraestructural de las uniones neuromusculares del músculo extensor largo de los dedos (M. extensor digitorum longus) del ratón
Fecha
2009-01-01Registro en:
International Journal of Morphology, v. 27, n. 3, p. 927-932, 2009.
0717-9502
0717-9367
10.4067/S0717-95022009000300045
2-s2.0-72549105310
9000303009545712
0000-0001-6052-2626
Autor
Universidade Estadual Paulista (UNESP)
Institución
Resumen
The neuromuscular junction of the extensor digitorum longus muscle of fingers was analyzed in 21 young (three months) and old (from six to 25 months) mice, from both genders. Morphologic changes were found throughout the mouse life, being more frequent and visible with aging. According with the data described in the literature consulted and the observations taken in this research, it becomes clear that a continuous process of morphological remodeling occurs in all neuromuscular ultrastructural junctions of the extensor digitorum longus muscle of fingers, during the life of the animal. Theses changes are characterized by figures of myelin in the cytoplasm of Schwann cells, pleomorphic and multivesiclar bodies, mitochondrias with morphologically altered crests in the axon terminal and degenerated junction folders. Coated vesicles are common in older animals and rare in young animals.