Artículos de revistas
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment
Fecha
2014-01-01Registro en:
European Review for Medical and Pharmacological Sciences, v. 18, n. 9, p. 1391-1397, 2014.
1128-3602
2-s2.0-84902136491
Autor
Pharmacological Research in Dentistry Group, Faculty of Dentistry, University of Granada
Extremadura Health Service, Cáceres Health Center Area SES
Faculty of Odontology of Araçatuba, University of the State of São Paulo
Faculty of Medicine and Dentistry, University of Murcia
Institución
Resumen
Bisphosphonates are a type of drugs known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and, thus, bone resorption. Bisphosphonates are, therefore, very widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw and this is their principal risk. A 75-year-old woman received dental treatment before starting intravenous BP therapy for a breast cancer. She started intravenous bisphosphonate treatment with monthly protocol and after two years the patient presented a wound compatible with osteonecrosis of the jaw.