Minimal structural changes determine full and partial nicotinic receptor agonist activity for nicotine analogues

dc.creatorGonzalez-Gutierrez J.P.
dc.creatorHodar M.
dc.creatorViscarra F.
dc.creatorPaillali P.
dc.creatorGuerra-Díaz N.
dc.creatorPessoa-Mahana H.
dc.creatorHernández-Morantes J.J.
dc.creatorPérez-Sánchez H.
dc.creatorBermúdez I.
dc.creatorReyes-Parada M.
dc.creatorIturriaga-Vásquez P.
dc.date.accessioned2020-09-02T22:19:21Z
dc.date.accessioned2022-11-08T20:28:06Z
dc.date.available2020-09-02T22:19:21Z
dc.date.available2022-11-08T20:28:06Z
dc.date.created2020-09-02T22:19:21Z
dc.date.issued2019
dc.identifier24, 15, -
dc.identifier14203049
dc.identifierhttps://hdl.handle.net/20.500.12728/4713
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5146699
dc.languageen
dc.publisherMDPI AG
dc.subjectDocking
dc.subjectPartial agonist
dc.subjectPyrrolidine ethers
dc.subjectα4β2 nAChR
dc.subjectnicotine
dc.subjectnicotinic agent
dc.subjectnicotinic receptor
dc.subjectprotein binding
dc.subjectbinding competition
dc.subjectchemical structure
dc.subjectchemistry
dc.subjectconformation
dc.subjectdose response
dc.subjecthuman
dc.subjectkinetics
dc.subjectmolecular docking
dc.subjectmolecular dynamics
dc.subjectstructure activity relation
dc.subjectBinding, Competitive
dc.subjectDose-Response Relationship, Drug
dc.subjectHumans
dc.subjectKinetics
dc.subjectMolecular Conformation
dc.subjectMolecular Docking Simulation
dc.subjectMolecular Dynamics Simulation
dc.subjectMolecular Structure
dc.subjectNicotine
dc.subjectNicotinic Agonists
dc.subjectProtein Binding
dc.subjectReceptors, Nicotinic
dc.subjectStructure-Activity Relationship
dc.titleMinimal structural changes determine full and partial nicotinic receptor agonist activity for nicotine analogues
dc.typeArticle


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