Synthesis of novel nicotinic ligands with multimodal action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters

dc.creatorGonzález-Gutiérrez J.P.
dc.creatorPessoa-Mahana H.A.
dc.creatorIturriaga-Vásquez P.E.
dc.creatorReyes-Parada M.I.
dc.creatorGuerra-Díaz N.E.
dc.creatorHodar-Salazar M.
dc.creatorViscarra F.
dc.creatorPaillali P.
dc.creatorNúñez-Vivanco G.
dc.creatorLorca-Carvajal M.A.
dc.creatorMella-Raipán J.
dc.creatorZúñiga M.C.
dc.date.accessioned2020-09-02T22:19:23Z
dc.date.accessioned2022-11-08T20:23:16Z
dc.date.available2020-09-02T22:19:23Z
dc.date.available2022-11-08T20:23:16Z
dc.date.created2020-09-02T22:19:23Z
dc.date.issued2019
dc.identifier24, 20, -
dc.identifier14203049
dc.identifierhttps://hdl.handle.net/20.500.12728/4724
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5144772
dc.languageen
dc.publisherMDPI AG
dc.subjectAffinity
dc.subjectAllosteric modulators
dc.subjectAllosteric modulators
dc.subjectDAT
dc.subjectNAChR
dc.subjectSERT
dc.subjectα4β2
dc.subjectacetylcholine
dc.subjectdopamine
dc.subjectdopamine receptor stimulating agent
dc.subjectdopamine transporter
dc.subjectester
dc.subjectligand
dc.subjectnicotine
dc.subjectnicotinic agent
dc.subjectnicotinic receptor
dc.subjectnicotinic receptor alpha4beta2
dc.subjectpyrrolidine
dc.subjectpyrrolidine derivative
dc.subjectserotonin transporter
dc.subjectallosterism
dc.subjectbinding site
dc.subjectchemistry
dc.subjectHEK293 cell line
dc.subjecthuman
dc.subjectmolecular docking
dc.subjectradioassay
dc.subjectstructure activity relation
dc.subjectsynthesis
dc.subjectAcetylcholine
dc.subjectAllosteric Regulation
dc.subjectBinding Sites
dc.subjectDopamine
dc.subjectDopamine Agonists
dc.subjectDopamine Plasma Membrane Transport Proteins
dc.subjectEsters
dc.subjectHEK293 Cells
dc.subjectHumans
dc.subjectLigands
dc.subjectMolecular Docking Simulation
dc.subjectNicotine
dc.subjectNicotinic Agonists
dc.subjectPyrrolidines
dc.subjectRadioligand Assay
dc.subjectReceptors, Nicotinic
dc.subjectSerotonin Plasma Membrane Transport Proteins
dc.subjectStructure-Activity Relationship
dc.titleSynthesis of novel nicotinic ligands with multimodal action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters
dc.typeArticle


Este ítem pertenece a la siguiente institución