Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype

dc.creatorTramutola A.
dc.creatorPupo G.
dc.creatorDi Domenico F.
dc.creatorBarone E.
dc.creatorArena A.
dc.creatorLanzillotta C.
dc.creatorBroekaart D.
dc.creatorBlarzino C.
dc.creatorHead E.
dc.creatorButterfield D.A.
dc.creatorPerluigi M.
dc.date.accessioned2020-09-02T22:29:23Z
dc.date.accessioned2022-11-08T20:17:56Z
dc.date.available2020-09-02T22:29:23Z
dc.date.available2022-11-08T20:17:56Z
dc.date.created2020-09-02T22:29:23Z
dc.date.issued2016
dc.identifier52, 1, 359-371
dc.identifier13872877
dc.identifierhttps://hdl.handle.net/20.500.12728/6436
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5142496
dc.languageen
dc.publisherIOS Press
dc.subjectApoptosis
dc.subjectcaspase
dc.subjectp53
dc.subjectsirtuins
dc.subjecttrisomy 21
dc.subjectTs65Dn mouse model
dc.subjectcaspase 3
dc.subjectheat shock protein 27
dc.subjectheat shock protein 70
dc.subjectnicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1
dc.subjectperoxisome proliferator activated receptor gamma coactivator 1alpha
dc.subjectprotein Bax
dc.subjectprotein MDM2
dc.subjectprotein p21
dc.subjectprotein p53
dc.subjectsirtuin 1
dc.subjectsirtuin 2
dc.subjectprotein p53
dc.subjectadult
dc.subjectAlzheimer disease
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectapoptosis
dc.subjectArticle
dc.subjectcontrolled study
dc.subjectDown syndrome
dc.subjectfemale
dc.subjectfrontal cortex
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectmale
dc.subjectmouse
dc.subjectneuropathology
dc.subjectnonhuman
dc.subjectoxidative stress
dc.subjectphenotype
dc.subjectpriority journal
dc.subjectprotein acetylation
dc.subjectprotein phosphorylation
dc.subjectupregulation
dc.subjectacetylation
dc.subjectAlzheimer disease
dc.subjectanimal
dc.subjectapoptosis
dc.subjectC3H mouse
dc.subjectC57BL mouse
dc.subjectdisease model
dc.subjectDown syndrome
dc.subjectfrontal lobe
dc.subjectimmunoprecipitation
dc.subjectmetabolism
dc.subjectmiddle aged
dc.subjectpathology
dc.subjectphenotype
dc.subjectphosphorylation
dc.subjectphysiology
dc.subjecttransgenic mouse
dc.subjectWestern blotting
dc.subjectyoung adult
dc.subjectAcetylation
dc.subjectAlzheimer Disease
dc.subjectAnimals
dc.subjectApoptosis
dc.subjectBlotting, Western
dc.subjectDisease Models, Animal
dc.subjectDown Syndrome
dc.subjectFemale
dc.subjectFrontal Lobe
dc.subjectHumans
dc.subjectImmunoprecipitation
dc.subjectMale
dc.subjectMice, Inbred C3H
dc.subjectMice, Inbred C57BL
dc.subjectMice, Transgenic
dc.subjectMiddle Aged
dc.subjectPhenotype
dc.subjectPhosphorylation
dc.subjectTumor Suppressor Protein p53
dc.subjectYoung Adult
dc.titleActivation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype
dc.typeArticle


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