Increased competition in the global market place has forced companies to seek better products and services, with lower cost and in a market suitable time. According to the holonic manufacturing paradigm, those requirements could be achieved if a reconfigurable enterprise were developed from autonomous and intelligent agents that dynamically interact with each other. This system should be able to automatically organize itself in such a way that its functions were arranged to achieve the finest performance. But if this system was really effective and proactive, it should search for functionalities beyond its own boundaries; it could obtain better competitive edges if it were gathering external partners that do some tasks in better ways than it ordinarily does by itself. Hence, the virtual supply chain, in its sense of distributed enterprises aggregation, can be a natural result of holonic manufacturing systems. This paper illustrates the advantages of using holonic concepts in the virtual supply chain realm through the self-organization of dynamic systems, exploring the holonic paradigm as a catalyst to enable this aggregation. Hence holonic manufacturing models will be seen as important references to virtual supply chains