| dc.contributor | Quirarte, G.L., Facultad de Psicología, Universidad de Guadalajara, Apartado Postal 70-250, Mexico D.F. 04510, Mexico; Cruz-Morales, S.E., ENEP-Iztacala, Universidad National Autónoma de México, Apartado Postal 70-250, Mexico D.F. 04510, Mexico; Diaz Del Guante, M.A., Centro de Estudios Psicológicos, Universidad Veracruzana, Apartado Postal 70-250, Mexico D.F. 04510, Mexico; Garcia, M., Departamento de Fisiología, Facultad de Meditina, Universidad National Autónoma de México, Apartado Postal 70-250, Mexico D.F. 04510, Mexico; Prado-Alcala, R.A., Departamento de Fisiología, Facultad de Meditina, Universidad National Autónoma de México, Apartado Postal 70-250, Mexico D.F. 04510, Mexico | |
| dc.description.abstract | Administration of antimuscarinic drugs induces amnesia of aversively motivated behaviors. However, when relatively high intensities of footshock are used during training (over-reinforcement), animals become protected against such amnesic state. Moreover, the protective effect is established in a none-or-all fashion i.e., within a series of increasing intensities a minute augmentation of footshock intensity is sufficient to reach the protective threshold. In the present experiment it was found that very low intensities of aversive stimulation (under-reinforcement), sufficient to produce learning, also protected animals from scopolamine-induced amnesia. These results suggest that acetylcholine is critically involved in memory consolidation of passive avoidance, but only within a limited range of training intensities. © 1993. | |
