dc.contributorSalinas-Torres, V.M., Department of Medical Genetics, Civil Hospital of Guadalajara Fray Antonio Alcalde and University of Guadalajara, Hospital No. 278, Col. El Retiro, Guadalajara, Jalisco 44280, Mexico; Pérez-García, N., Department of Radiology, Civil Hospital of Guadalajara Fray Antonio Alcalde and University of Guadalajara, Guadalajara, Jalisco, Mexico; Pérez-García, G., Department of Medical Genetics, Civil Hospital of Guadalajara Fray Antonio Alcalde and University of Guadalajara, Hospital No. 278, Col. El Retiro, Guadalajara, Jalisco 44280, Mexico
dc.creatorSalinas-Torres, V.M.
dc.creatorPerez-García, N.
dc.creatorPerez-García, G.
dc.date.accessioned2015-09-15T17:32:32Z
dc.date.accessioned2022-11-02T15:06:06Z
dc.date.available2015-09-15T17:32:32Z
dc.date.available2022-11-02T15:06:06Z
dc.date.created2015-09-15T17:32:32Z
dc.date.issued2014
dc.identifierhttp://hdl.handle.net/20.500.12104/40145
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84878498781&partnerID=40&md5=d2f3709151f6c7470b2f17536cf1c40f
dc.identifier10.1097/SCS.0b013e31828609cb
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5009130
dc.description.abstractIn this series the authors evaluate clinical, cytogenetic, environmental and inheritance characteristics of neonates with VACTERL association. Twenty-six patients were diagnosed with VACTERL association and had a normal somatometric profile. Fifty-eight percent cases were males. The frequency of each component was: vertebral defects (V), 77 %; anal atresia (A), 62 %; tracheo-esophageal fistula/esophageal atresia (TEF/EA), 58 %; renal anomalies (R), 58 %; limb abnormalities (L), 50 %, and cardiac malformations (C), 42 %. The most frequent combination was VAR (n = 3). Sixteen patients had non-VACTERL anomalies such as bilateral cryptorchidism (n = 4). Two probands (8 %) had first or second-degree relatives with two components. Five patients (19 %) had environmental factors that interacted with ocurrence of VACTERL association. All patients had a normal karyotype. This study contributes to a better characterization of VACTERL phenotype in neonatal period. In spite of predominant sporadic occurrence, underlying genetic susceptibility and environmental influences point to a complex interplay between genes and environmental factors in VACTERL association. " 2014 Dr. K C Chaudhuri Foundation.",,,,,,"10.1007/s12098-014-1493-5",,,"http://hdl.handle.net/20.500.12104/40129","http://www.scopus.com/inward/record.url?eid=2-s2.0-84903854259&partnerID=40&md5=5b6f75e03d56aa28cfcd12d71b03b21b
dc.description.abstracthttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25008186",,,,,,,,"The Indian Journal of Pediatrics",,,,,,"Scopus
dc.description.abstractWOS
dc.description.abstractMEDLINE",,,,"Index Medicus",,"Clinical; Cytogenetic; Environmental; Inheritance; Neonates; VACTERL association",,,,,,"Clinical, Cytogenetic, Environmental and Inheritance Findings in Mexican Neonates with VACTERL Association",,"Article in Press" "41924","123456789/35008",,"Cantú-Cantú, M.Z., Hospital Pediátrico Tacubaya, Mexico City, Mexico; Lyra-González, I., Instituto de Biología Molecular en Medicina y Terapia Gúnica, Departamento de Biología Molecular y Genómica, CUCS, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara, Jalisco 44281, Mexico; Armendáriz-Borunda, J., Instituto de Biología Molecular en Medicina y Terapia Gúnica, Departamento de Biología Molecular y Genómica, CUCS, Universidad de Guadalajara, Sierra Mojada #950, Guadalajara, Jalisco 44281, Mexico, Innovare, Guadalajara, Mexico",,"Cantu-Cantu, M.Z.
dc.description.abstractLyra-Gonzalez, I.
dc.description.abstractArmendariz-Borunda, J.",,"2013",,"Background: This case report assesses the effectiveness of surgery plus pirfenidone (PFD) as a concomitant therapyinthe management of facial trauma after severe dog bite. Methods: A 16-month-old female patient who suffered a severe attack by a big-sized dog (Rottweiler) in the midface area was managed with surgery/PFD combination and followed up for 20 months to evaluate the efficacy to control, prevent, and improve injury sequels. Results: Surgery/PFD combination offered a good complementary therapy downregulating inflammatory activity, improving blood supply, and activating cytokine modulation and collagen synthesis/biosynthesis (scar control). No side effects were reported in this case report. Conclusions: Surgery/PFD management for severe facial dog bites represents a safe and effective therapeutic option to protect and improve a patient's quality of life, minimizing long-time sequels. Copyright " 2013 by Mutaz B. Habal, MD.
dc.relationScopus
dc.relationWOS
dc.relationJournal of Craniofacial Surgery
dc.relation24
dc.relation2
dc.relation675
dc.relation678
dc.titleCoadjuvant treatment with surgery and pirfenidone in severe facial trauma due to dog bite
dc.typeArticle


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