The Human Brain Subventricular Zone: Stem Cells in This Niche and Its Organization

dc.contributorQuiñones-Hinojosa, A., Stem Cell Laboratory, Brain Tumor Program, Department of Neurological Surgery, 1550 Orleans Street, Baltimore, MD 21231, United States; Sanai, N., Brain Tumor Research Center, Developmental Stem Cell Biology Program, Department of Neurological Surgery, 505 Parnassus Avenue, San Francisco, CA 94143-0112, United States; Gonzalez-Perez, O., Department of Neuroscience, Centro Universitario de Ciencias de la Salud, University of Guadalajara, Guadalajara, Jal. 44340, Mexico; Garcia-Verdugo, J.M., Instituto Cavanilles, Centro de Investigación Principe Felipe, Universidad de Valencia, Burjassot, 46100 Valencia, Spain
dc.creatorQuinones-Hinojosa, A.
dc.creatorSanai, N.
dc.creatorGonzalez-Perez, O.
dc.creatorGarcia-Verdugo, J.M.
dc.date.accessioned2015-11-19T18:57:56Z
dc.date.accessioned2022-11-02T14:55:08Z
dc.date.available2015-11-19T18:57:56Z
dc.date.available2022-11-02T14:55:08Z
dc.date.created2015-11-19T18:57:56Z
dc.date.issued2007
dc.identifierhttp://hdl.handle.net/20.500.12104/71382
dc.identifier10.1016/j.nec.2006.10.013
dc.identifierhttp://www.scopus.com/inward/record.url?eid=2-s2.0-33846522223&partnerID=40&md5=70516a18e7c0e1076520ae3d234c9111
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5006306
dc.description.abstractTaken together, these observations offer direct evidence that this germinal region is not only organized differently but contains cells with astrocytic characteristics that function as neural stem cells. Considering the size of the human lateral ventricular system, this work suggests that a substantial number of neural stem cells exist in the adult brain throughout life. Understanding the organization of the adult human SVZ represents a necessary first step in understanding the cellular proliferation, precursor migration, and neurogenic niche of the largest known germinal region in the adult human brain-a foundation on which to develop novel neuroregenerative therapies. © 2007 Elsevier Inc. All rights reserved.
dc.relationNeurosurgery Clinics of North America
dc.relation18
dc.relation1
dc.relation15
dc.relation20
dc.relationScopus
dc.relationWOS
dc.titleThe Human Brain Subventricular Zone: Stem Cells in This Niche and Its Organization
dc.typeReview


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