| dc.contributor | Ruiz-Sandoval, J.L., Servicio de Neurolog�a y Neurocirug�a, Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico, Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, JAL, Mexico; Chiquete, E., Servicio de Neurolog�a y Neurocirug�a, Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico; G�rate-Carrillo, A., Facultad de Ciencias, Universidad Aut�noma de Baja California, Ensenada, Mexico; Ochoa-Guzm�n, A., Servicio de Neurolog�a y Neurocirug�a, Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico; Arauz, A., Stroke Clinic, Instituto Nacional de Neurolog�a y Neurocirug�a, INNN, M�xico DF, Mexico; Le�n-Jim�nez, C., Servicio de Neurolog�a, Hospital Valent�n G�mez Far�as; ISSSTE, Zapopan, Mexico; Carrillo-Loza, K., Servicio de Neurolog�a y Neurocirug�a, Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico; Murillo-Bonilla, L.M., Terapia Endovascular, Instituto Panvascular de Occidente, Universidad Aut�noma de Guadalajara, Guadalajara, JAL, Mexico; Villarreal-Careaga, J., Servicio de Neurolog�a, Hospital General de Culiac�n, Culiac�n, SIN, Mexico; Barinagarrementer�a, F., Servicio de Neurolog�a, Hospital �ngeles de Quer�taro, Mexico; Cant�-Brito, C., Servicio de Neurolog�a, Instituto Nacional de Ciencias M�dicas y Nutrici�n Salvador Zubir�n, M�xico DF, Mexico | |
| dc.description.abstract | Introduction. Scarce information exists on intracerebral hemorrhage (ICH) in Latin America, and the existent is derived from single-center registries with non-generalizable conclusions. The aim of this study is to describe the frequency, etiology, management and outcome of ICH in Mexico. Patients and methods. We studied consecutive patients with ICH pertaining to the National Multicenter Registry on Cerebrovascular Disease (RENAMEVASC), conducted in 25 centers from 14 states of Mexico. The Intracerebral Hemorrhage Grading Scale (ICH-GS) at admission was used to assess prognosis at 30 days follow-up. Results. Of 2,000 patients with acute cerebrovascular disease registered in RENAMEVASC, 564 (28%) had primary ICH (53% women; median age: 63 years; interquartile range: 50-75 years). Hypertension (70%), vascular malformations (7%) and amyloid angiopathy (4%) were the main etiologies. In 10% of cases etiology could not be determined. Main ICH locations were basal ganglia (50%), lobar (35%) and cerebellum (5%). Irruption into the ventricular system occurred in 43%. Median score of ICH-GS was 8 points: 49% had 5-7 points, 37% had 8-10 points and 15% had 11-13 points. The 30-day case fatality rate was 30%, and 31% presented severe disability. The 30-day survival was 92% for patients with ICH-GS 5-7 points, whereas it decreased to 27% in patients with ICH-GS 11-13 points. Conclusions. In Mexico, ICH represents about a third of the forms of acute cerebrovascular disease, and the majority of patients present severe disability or death at 30 days of follow-up. Hypertension is the main cause; hence, control of this important cardiovascular risk factor should reduce the health burden of ICH. � 2011 Revista de Neurologia. | |
