Artículo
A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma
Fecha
2013Registro en:
Bologna Molina, R, Salazar Rodríguez, S, Bedoya Borella, A. y otros . "A Histopathological and Immunohistochemical analysis of ameloblastic fibrodentinoma"Case Reports in Pathology Volumen 2013. [en línea] 2013. doi.org/10.1155/2013/604560
doi.org/10.1155/2013/604560
Autor
Bologna Molina, Ronell
Salazar Rodríguez, Sirced
Bedoya Borella, Ana María
Carreón Burciaga, Ramón Gil
Tapia Repetto, Gabriel
Molina Frechero, Nelly
Institución
Resumen
Ameloblastic fibrodentinoma (AFD) is considered a mixed odontogenic tumor that is characterized by conserved epithelial and ectomesenchymal neoplastic components. AFD is composed of long narrow cords and islands of odontogenic epithelium; the epithelial strands lie in a myxoid cell-rich ectomesenchymal tissue with stellate-shaped fibroblasts that exhibit long slender cytoplasmic extensions that resemble dental papilla. The lesions show the presence of dysplastic dentin. Although AFD is a rare entity and its very existence is not completely accepted, based on the extent of histodifferentiation, it is considered to represent a stage between ameloblastic fibroma and ameloblastic fibroodontoma.This study aimed to provide a histopathological and immunohistochemical characterization of this infrequent tumor. A large panel of antibodies including amelogenin, Ck 19, calretinin, syndecan-1, E-cadherin, MSH2, histone H3, and Ki-67 was used to illustrate the nature of the tumor.