Echinococcus vogeli and Echinococcus oligarthrus, new world autochthonous species are responsible for polycystic echinococcosis. The purpose of this work is the presentation of a polycystic hepatic echinococcosis case due to Echinococcus vogeli in an indigenous inhabitant of the Venezuelan amazon area. The patient presented a penetrating abdominal pain, hepatomegalia and marked eosinophilia. Liver imaging (echosonogram and computerized axial tomography) as well an echinococcosis positive serology (ELISA and Western- blot) contributed to the pre-surgical diagnosis. Treatment with albendazol was initiated previous to surgery. The cephalic hooks of the protoscolexes were studied and it was determined that their mean length, morphology and proportions corresponded to E. vogeli. The patient evolved satisfactorily and continued albendazol treatment during six months. In the Venezuelan amazon area there are still numerous wilds animals which are intermediate and final hosts of this cestode. Cuniculus paca or lapa, Dasyprocta aguti or Venezuelan aguti, Speothus veneticus, wild dogs and wild cats, are natural host of both species. We suggest considering the possibility of polycystic echinococcosis in native individuals with polycystic imagining and liver calcifications (and eosinophilia) who come from Venezuelan tropical forests. Nevertheless, it should be remembered that domestic dogs and cats are responsible of human infections.Equinococosis hepática poliquística autóctonaAl Consejo de Desarrollo Científico y Humanístico (CDCH) de la Universidad Central de Venezuela por el financiamiento para la asistencia a XVII FLAP en Mar del Plata, Argentina, del 23 al 26 de noviembre de 2005, donde se presentaron los resultados preliminares de este trabajo.