Article
Adenocarcinoma pleomórfico de células giganates de vías biliares(osteoclastoma like)
Fecha
2015-06Autor
Quezada Morales, Manuel Emilio
Alvarado Corral, Raúl Francisco
Jara Sánchez, Laura Fabiola
Institución
Resumen
Osteoclast-type giant cells (CGTO) of the pancreas
are not frequent originally described by
Rosaien 1968, characterized by osteoclasts
that are giant cells identical mononuclear
stromal cells in bone tumors observed. Since
then, there are few reports of tumors containing
giant cells in other anatomic locations.
The CGTO can be distinguished from the pleomorphic
type giant cells (CGTP), due to the
lack of an associated marked nuclear pleomorphism.
Often a pancreatic carcinoma
histologically recognizable CGTO accompanies,
leading to a bad result. CGTO pure forms
have a better prognosis because it takes
a long time to develop metastases, but this
form is very rare, with few cases reported in
the English literature. Most times the benign
diagnosis of these tumors based on immunohistochemistry
evaluation is discussed.
This case is a female patient 56 years old with
picture characterized by cramping pain that
improves with antispasmodics, several months
of evolution, with periods of remission and
exacerbation. A physical exam features: light
skin and mucous subictérico dye, abdominal
level: diffusely painful abdomen without viseromegalias
or palpable masses