Antibacterial Activity and Kinetic Release of Laureliopsis philippiana (Looser) Essential Oil from Nanostructured Porous Silicon with Surface-Functionalization Alternatives

dc.creatorMartin, Andres Perez San
dc.creatorUribe, Karina
dc.creatorHernandez Montelongo, Jacobo
dc.creatorNaveas, Nelson
dc.creatorManso Silvan, Miguel
dc.creatorOyarzun, Patricio
dc.creatorDiaz Garcia, Victor
dc.creatorContreras, Braulio
dc.creatorRecio Sanchez, Gonzalo
dc.date2022
dc.date2022-10-04T21:36:38Z
dc.date2022-10-04T21:36:38Z
dc.date.accessioned2022-10-18T14:52:09Z
dc.date.available2022-10-18T14:52:09Z
dc.identifierAPPLIED SCIENCES-BASEL,Vol.12,,2022
dc.identifierhttps://repositoriodigital.uct.cl/handle/10925/4771
dc.identifier10.3390/app12168258
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4443992
dc.descriptionIn this work, the antibacterial activity of Laureliopsis philippiana (Looser) essential oil was studied, and its kinetic release performance using different surface-functionalized nanostructured porous silicon (nPSi) was analyzed. Experimental results showed the high inhibitory effect of Laureliopsis philippiana essential oil against Staphylococcus aureus and Klebsiella pneumoniae. In addition, the essential oil was successfully loaded into different kinds of functionalized nPSi. FTIR measurements indicated the formation of stable complexes in the nPSi functionalization process. Specifically, chemical oxidized nPSi (nPSi-Ox), 3-aminopropyltriethoxysilane functionalized nPSi (nPSi-APTS), undecylenic acid-functionalized nPSi (nPSi-UAc), chitosan (nPSi-Chi) and beta-cyclodextrin (nPSi-beta CD) polymer functionalization on nPSi were studied. nPSi-Ox, nPSi-APTS, and nPSi-UAc were covalent functionalization, and nPSi-Chi and nPSi-beta CD were obtained by electrostatic attachment. The kinetic study demonstrated a controlled release of up to 4 h for all the samples following a quasi-Fickian diffusion mechanism. Moreover, the use of functionalized nPSi-APTS and nPSi-UAc structures allows a more controlled kinetic release of Laureliopsis philippiana essential oil in comparison to the rest of the functionalization, increasing its availability and exposure to the environment.
dc.languageen
dc.publisherMDPI
dc.sourceAPPLIED SCIENCES-BASEL
dc.subjectnanostructured porous silicon
dc.subjectsurface functionalization
dc.subjectessential oil
dc.subjectLaureliopsis philippiana
dc.subjectantibacterial activity
dc.titleAntibacterial Activity and Kinetic Release of Laureliopsis philippiana (Looser) Essential Oil from Nanostructured Porous Silicon with Surface-Functionalization Alternatives
dc.typeArticle


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