| dc.description.abstract | Currently, most vaccines available on the market are for parental use; however, this may
not be the best option on several occasions. Mucosal routes of administration such as intranasal,
sublingual, and buccal generate great interest due to the benefits they offer. These range from
increasing patient compliance to inducing a more effective immune response than that achieved
through conventional routes. Due to the activation of the common mucosal immune system, it is
possible to generate an effective systemic and local immune response, which is not achieved through
parenteral administration. Protection against pathogens that use mucosal entry routes is provided by
an effective induction of mucosal immunity. Mucosal delivery systems are being developed, such
as films and microneedles, which have proven to be effective, safe, and easy to administer. These
systems have multiple advantages over commonly used injections, which are simple to manufacture,
stable at room temperature, painless for the patient since they do not require puncture. Therefore,
these delivery systems do not require to be administered by medical personnel; in fact, they could be
self-administered. | |
