info:eu-repo/semantics/article
Test–retest reliability of the Friedreich’s ataxia rating scale
Fecha
2020-09Registro en:
Rummey, Christian; Zesiewicz, Theresa A.; Perez Lloret, Santiago; Farmer, Jennifer M.; Pandolfo, Massimo; et al.; Test–retest reliability of the Friedreich’s ataxia rating scale; Wiley Blackwell Publishing, Inc; Annals of Clinical and Translational Neurology; 7; 9; 9-2020; 1708-1712
2328-9503
CONICET Digital
CONICET
Autor
Rummey, Christian
Zesiewicz, Theresa A.
Perez Lloret, Santiago
Farmer, Jennifer M.
Pandolfo, Massimo
Lynch, David R.
Resumen
The modified Friedreich Ataxia Rating Scale (mFARS) is a disease specific, exam-based neurological rating scale commonly used as a outcome measure in clinical trials. While extensive clinimetric testing indicates it’s validity in measuring disease progression, formal test–retest reliability was lacking. To fill this gap, we acquired results from screening and baseline visits of several large clinical trials and calculated intraclass correlation coefficients, coefficients of variance, standard error, and the minimally detectable changes. This study demonstrated excellent test–retest reliability of the mFARS, and it’s upright stability subscore.