Prognostic significance of α‐ and β2‐adrenoceptor gene expression in breast cancer patients

Rivero, Ezequiel Mariano; Martinez, Leandro Marcelo; Bruque, Carlos David; Gargiulo, Lucía; Bruzzone, Ariana; Luthy, Isabel Alicia

info:eu-repo/semantics/article

Fecha

2019-07

Registro en:

Rivero, Ezequiel Mariano; Martinez, Leandro Marcelo; Bruque, Carlos David; Gargiulo, Lucía; Bruzzone, Ariana; et al.; Prognostic significance of α‐ and β2‐adrenoceptor gene expression in breast cancer patients; The British Pharmacological Society; British Journal Of Clinical Pharmacology; 85; 9; 7-2019; 2143-2154

0306-5251

http://hdl.handle.net/11336/106323

1365-2125

CONICET Digital

CONICET

https://repositorioslatinoamericanos.uchile.cl/handle/2250/4412019

Autor

Rivero, Ezequiel Mariano

Martinez, Leandro Marcelo

Bruque, Carlos David

Gargiulo, Lucía

Bruzzone, Ariana

Luthy, Isabel Alicia

Institución

Consejo Nacional de Investigaciones Científicas y Tecnológicas (Argentina)

Resumen

Breast cancer is the most frequently diagnosed and leading cause of cancer death among women worldwide. It was classified within molecular intrinsic subtypes: luminal A, luminal B, human epidermal growth factor receptor 2‐enriched and basal‐like. Epinephrine and norepinephrine, released during stress, bind to adrenoceptors. α2‐adrenoceptors are encoded by the ADRA2A , ADRA2B and ADRA2C genes and β2 by ADRB2 .

Materias

ADRENOCEPTORS

BREAST CANCER PATIENTS

PROGNOSTIC FACTORS

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